Cladielloides A and B: New Eunicellin-Type Diterpenoids from an Indonesian Octocoral Cladiella sp

نویسندگان

  • Yung-Husan Chen
  • Chia-Ying Tai
  • Tsong-Long Hwang
  • Ching-Feng Weng
  • Jan-Jung Li
  • Lee-Shing Fang
  • Wei-Hsien Wang
  • Yang-Chang Wu
  • Ping-Jyun Sung
چکیده

Two new eunicellin-type diterpenoids, cladielloides A (1) and B (2), which were found to possess a 2-hydroxybutyroxy group in their structures, were isolated from an Indonesian octocoral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods. Cladielloide B (2) exhibited moderate cytotoxicity toward CCRF-CEM tumor cells and this compound displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2010